Magnesium Diglycinate Absorption

On November 30, 2010, in Minerals, Reviews, by Andrea

Yup.  More damning evidence against Journey.  Oops.  And folks?  This isn’t good.

This comes from a paper about magnesium chelation.

The magnesium chelate used is magnesium diglycinate.  The supporting documentation that Albion uses is a study that compares it to magnesium oxide in patients with ileal resection, mostly due to Crohn’s disease.

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On January 21, 2010, in Fat Solubles, Minerals, Vitamins, Water Solubles, by Andrea

Just giving you proof — I practice what I preach.

This is my week’s worth of vitamins.  Well, six days’ worth.  I’ve lost the 7th day somewhere and I really like this set, so I make do with what I’ve got.

My week, in perspective.

Each day may be divided into 4 compartments, but that does not mean that I only take vitamins 4 times per day.  Several compartments have 2 doses in them.

I just thought that I’d put this out there — that I do, in fact, take the vitamins that I write about.

Magnesium bioavailability

On December 20, 2009, in Minerals, by Andrea

From Journal of The American College of Nutrition:


Magnesium bioavailability from magnesium citrate and magnesium oxide

J. S. Lindberg, M. M. Zobitz, J. R. Poindexter and C. Y. Pak
Center for Mineral Metabolism and Clinical Research, University of Texas, Southwestern Medical Center, Dallas 75235.

This study compared magnesium oxide and magnesium citrate with respect to in vitro solubility and in vivo gastrointestinal absorbability. The solubility of 25 mmol magnesium citrate and magnesium oxide was examined in vitro in solutions containing varying amounts of hydrochloric acid (0-24.2 mEq) in 300 ml distilled water intended to mimic achlorhydric to peak acid secretory states. Magnesium oxide was virtually insoluble in water and only 43% soluble in simulated peak acid secretion (24.2 mEq hydrochloric acid/300 ml). Magnesium citrate had high solubility even in water (55%) and was substantially more soluble than magnesium oxide in all states of acid secretion. Reprecipitation of magnesium citrate and magnesium oxide did not occur when the filtrates from the solubility studies were titrated to pH 6 and 7 to stimulate pancreatic bicarbonate secretion. Approximately 65% of magnesium citrate was complexed as soluble magnesium citrate, whereas magnesium complexation was not present in the magnesium oxide system. Magnesium absorption from the two magnesium salts was measured in vivo in normal volunteers by assessing the rise in urinary magnesium following oral magnesium load. The increment in urinary magnesium following magnesium citrate load (25 mmol) was significantly higher than that obtained from magnesium oxide load (during 4 hours post-load, 0.22 vs 0.006 mg/mg creatinine, p less than 0.05; during second 2 hours post-load, 0.035 vs 0.008 mg/mg creatinine, p less than 0.05). Thus, magnesium citrate was more soluble and bioavailable than magnesium oxide.